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Opko won FDA approval for the drug in treatingsecondary hyperparathyroidism in June 2016. Sales are picking up for Rayaldee and should grow significantly in 2017. Opko projectsthat between 70% and 80% of Americans will be covered for Rayaldee by the middle of the year. The drug could reach peak annual sales of around $500 million -- over half of the company's total revenue in the first nine months of 2016. Last, but not least, is Opko's pipeline. Results from a mid-stage study evaluating a long-actingFVIIa replacement therapy for hemophilia patients should be announced in the first half of this year. Opko expects to start a phase 2b clinical study of oxyntomodulinin treating type 2 diabetes in the second half of 2017. Continue Reading Below ADVERTISEMENT The wild card in Opko's pipeline, though, is itsexperimental long-acting human growth hormone product hGH-CTP. Althoughthe primary endpoint wasn't met in a late-stage study targeting adults, Opko saw some outliers in the data that give it reason to be optimistic about moving forward.

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